Phytochemical analysis and the antioxidant and acetylcholinesterase inhibitory activity of propolis from northeastern Algeria
Pages 119 to 129
Cite this article
- OUAHAB, A.,
- GRARA, N.,
- MENAIAIA, K.,
- FUGALDI, Anne-Sophie
- and BENSOUICI, C.,
- Ouahab, A..,
- et al.
- Ouahab, A.,
- Grara, N.,
- Menaiaia, K.,
- Fugaldi, A.-S.
- and Bensouici, C.
https://doi.org/10.3166/phyto-2022-0359
Cite this article
- Ouahab, A.,
- Grara, N.,
- Menaiaia, K.,
- Fugaldi, A.-S.
- and Bensouici, C.
- Ouahab, A..,
- et al.
- OUAHAB, A.,
- GRARA, N.,
- MENAIAIA, K.,
- FUGALDI, Anne-Sophie
- and BENSOUICI, C.,
https://doi.org/10.3166/phyto-2022-0359
Propolis is a resinous substance produced by bees, consisting mainly of phenolic compounds with nutritional and therapeutic properties. It is formed through the mixing of tree and plant secretions collected by honey bees. The aim of this study was to assess the antioxidant and anticholinesterase activity of ethanolic and acetone propolis extracts from two sampling sites in the city of Souk Ahras (northeastern Algeria). The antioxidant activity of the extracts was determined using standard antioxidant assays (DPPH, ABTS, GOR, and CUPRAC), while anticholinesterase activity was assessed against acetylcholinesterase (AChE). Additionally, the total phenolic content (TPC), total flavonoid content (TFC), and condensed tannins content (CTC) were quantified. The propolis extracts exhibited a potent antioxidant and inhibitory activity, nearly matching that of the synthetic antioxidants used as standards (butylated hydroxytoluene [BHT] and butylated hydroxyanisole [BHA]). Furthermore, AChE activity was strongly inhibited in a dose-dependent manner by the propolis extracts. The propolis extracts demonstrated their richness in bioactive molecules capable of enhancing various biological activities and processes.