Journal article

Antioxidant and anti-mycotoxin activities of crude extracts from different organs of Bunium ferulaceum Sm.

Pages 94 to 101

Cite this article


  • Khaldi, A.,
  • Gouabi, R.-H.,
  • Mehdi, K.,
  • Mebarki, L.,
  • Moussaoui, A.
  • and Meddah, B.
(2023). Antioxidant and Anti-Mycotoxin Activities of Crude Extracts From Different Organs of Bunium Ferulaceum Sm. Phytothérapie, . 21(2), 94-101. https://doi.org/10.3166/phyto-2022-0303.

  • Khaldi, A..,
  • et al.
« Antioxidant and anti-mycotoxin activities of crude extracts from different organs of Bunium ferulaceum Sm. ». Phytothérapie, 2023/2 Vol. 21, 2023. p.94-101. CAIRN.INFO, stm.cairn.info/journal-phytotherapie-2023-2-3-page-94?lang=en.

  • KHALDI, A.,
  • GOUABI, R.H.,
  • MEHDI, K.,
  • MEBARKI, L.,
  • MOUSSAOUI, A.
  • and MEDDAH, B.,
2023. Antioxidant and anti-mycotoxin activities of crude extracts from different organs of Bunium ferulaceum Sm. Phytothérapie, 2023/2 Vol. 21, p.94-101. DOI : 10.3166/phyto-2022-0303. URL : https://stm.cairn.info/journal-phytotherapie-2023-2-3-page-94?lang=en.

https://doi.org/10.3166/phyto-2022-0303


English

The aim of this study was to determine the antioxidant and anti-mycotoxin activities of crude ethanolic extracts from various organs of the plant Bunium ferulaceum Sm. from western Algeria. First, we conducted a phytochemical screening of the plant’s leaves, seeds, and bark. The tests revealed the presence of several classes of chemical constituents and phenolic compounds. The quantitative estimation of the total phenol content, flavonoids, and coumarins was carried out using colorimetric methods. The highest total phenolic content was found in the leaf extract, with a TPC value of 51.22 ± 0.46 mg GAE/g. Flavonoids were identified as the main phenolic compounds in this extract, while coumarins were the main phenolic compounds in the bark extract. The antioxidant activity was evaluated using the DPPH method compared to the antioxidant ascorbic acid. The leaf extract showed a good scavenging activity, with an IC50 value of 0.11 ± 0.57 mg/ml. Anti-mycotoxin activity was tested against three pathogenic mycotoxin-producing fungi using the mycelial biomass assay and mycotoxigenic test. For all fungi tested, the leaf extract showed the best inhibitory activity against Penicillium expansum MTTC 1344 and Aspergillus flavus MTTC 2799, followed by the bark extract.