Recurrent cutaneous eosinophilic vasculitis in a child
Pages 180 to 181
Cite this article
- MARUO, Miho,
- NATSUGA, Ken,
- ANAN, Takashi,
- KODAMA, Kazuo
- and UJIIE, Hideyuki,
- Maruo, Miho.,
- et al.
- Maruo, M.,
- Natsuga, K.,
- Anan, T.,
- Kodama, K.
- and Ujiie, H.
https://doi.org/10.1684/ejd.2026.5043
Cite this article
- Maruo, M.,
- Natsuga, K.,
- Anan, T.,
- Kodama, K.
- and Ujiie, H.
- Maruo, Miho.,
- et al.
- MARUO, Miho,
- NATSUGA, Ken,
- ANAN, Takashi,
- KODAMA, Kazuo
- and UJIIE, Hideyuki,
https://doi.org/10.1684/ejd.2026.5043
Recurrent cutaneous eosinophilic vasculitis (RCEV), first described in 1994, is a rare disorder characterized by necrotizing vasculitis of small dermal vessels with prominent eosinophilic infiltration. It lacks systemic features such as fever, or asthma, which are commonly seen in systemic vasculitides [1]. RCEV typically affects adolescents and adults, and usually requires immunosuppressive therapy [2]. Here, we report a paediatric case of RCEV successfully managed without systemic treatment.
A 10-year-old Japanese boy presented with a one-year history of recurrent pruritic eruption on his right palm. There was no identifiable precipitating factor such as an insect bite. The lesion was refractory to both topical corticosteroids and topical and systemic antifungal agents. Physical examination revealed an erythematous plaque on the right thenar eminence and a subcutaneous nodule on the right leg (figure 1A, B). He reported no extracutaneous symptoms and had no history of allergic diseases. Laboratory tests showed mild peripheral eosinophilia (760/μL; normal: 40-400) and elevated serum IgE (482.1 IU/mL; normal <360.9). Antinuclear antibody was weakly positive (titre: 1:80) with a homogeneous and speckled pattern. MPO- and PR3-ANCA were negative. Chest radiography and computed tomography were unremarkable. Histopathological examination of both lesions revealed a dense eosinophilic infiltration within and around small dermal vessel walls, extending throughout the dermis, with extravasation of red blood cells …
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